Search results for " Waist-Hip Ratio"
showing 3 items of 3 documents
Influence of family history to type 2 diabetes on the body composition and homeostasis model assessment: a comparison between young active and sedent…
2006
Obiettivo. La storia familiare (family history, FH) per il diabete mellito (DM) di tipo 2 è un fattore di rischio per lo sviluppo della malattia, inducendo precoci modificazioni metaboliche e antropometriche in soggetti sedentari. Lo scopo di questo lavoro era studiare l’influenza di FH al DM sulla composizione corporea e sul metabolismo del glucosio in giovani uomini sedentari ed attivi. Metodi. In un’analisi trasversale, sono stati registrati dati antropometrici, composizione corporea (tramite BIA), insulina e glucosio plasmatici in 60 giovani siciliani sani (31 atleti e 29 soggetti sedentari); FH è stata definita come FH+ se il soggetto aveva riferito di avere almeno un membro della fami…
Familiar history and predictive risk factors to type 2 diabetes: a cross sectional study in young Sicilian subjects of both sexes.
2006
Aim. For many industrialised populations, family history to type 2 diabetes mellitus (DM) is a risk factor to the development of illness, inducing early anthropometric and metabolic modifications. Aim of this study was to confirm in Sicilian population the influence of family history to type 2 DM on anthropometric data and basal blood pressure, considering the different degrees of familiar history to illness. Methods. In a cohort of 680 young healthy Sicilian subjects (278 men and 402 women) we analysed the relations of family history degree of DM on anthropometric data, such as body mass index (BMI), waist/hip ratio (WHR) and triceps skinfold. Degree of family history of DM was defined as …
A Genome-Wide Screen for Interactions Reveals a New Locus on 4p15 Modifying the Effect of Waist-to-Hip Ratio on Total Cholesterol
2011
Recent genome-wide association (GWA) studies described 95 loci controlling serum lipid levels. These common variants explain ∼25% of the heritability of the phenotypes. To date, no unbiased screen for gene–environment interactions for circulating lipids has been reported. We screened for variants that modify the relationship between known epidemiological risk factors and circulating lipid levels in a meta-analysis of genome-wide association (GWA) data from 18 population-based cohorts with European ancestry (maximum N = 32,225). We collected 8 further cohorts (N = 17,102) for replication, and rs6448771 on 4p15 demonstrated genome-wide significant interaction with waist-to-hip-ratio (WHR) on …